Quality control and monitoring of Automatic Peptide Synthesizer

Quality control and monitoring of Automatic Peptide Synthesizer

Blog Article

Automatic Peptide Synthesizer are widely used in the fields of biochemistry, medicine and drug discovery. Peptide synthesis is a critical step in biotechnology research and drug development, so it is crucial to ensure its quality control and monitoring.

I. Quality control

1. Equipment performance verification

Before use, the equipment should be subjected to comprehensive performance validation, including synthesis efficiency, purity, accuracy and other aspects. By comparing the experiments and standard substances, assess whether the performance indexes of the equipment meet the experimental requirements. For equipment that does not meet the requirements, it should be adjusted or replaced.

2. Operation standardization

Operation standardization is the key to ensure the quality of automatic peptide synthesizer. Operators should be trained professionally and familiar with the working principle, operation steps and precautions of the equipment. In the operation process, they should strictly follow the operation regulations to avoid quality problems caused by improper operation.

3. Raw material quality control

The quality of raw materials directly affects the effect of peptide synthesis. Therefore, the quality control of raw materials should be strictly carried out, including the evaluation of suppliers and the inspection of raw materials. The use of raw materials that do not meet the quality requirements should be prohibited.

4. Process control

In the process of peptide synthesis, key steps should be monitored, such as reaction time, reaction temperature, catalyst concentration and so on. Through the control of process parameters, the quality and stability of peptide synthesis can be ensured.